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Drug Addiction Articles
Related Resources
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Facts About Prescription Drug Abuse and Addiction
Prescription drugs can help patients manage chronic or severe pain, restore
emotional or behavioral balance, control sleep disorders, or fight obesity.
When prescription medications are abused, however, the consequences-including
addiction-can be dangerous, even deadly. NIDA's newest Research Report
focuses on the risks associated with abuse of three classes of commonly
abused prescription drugs: opioids; central nervous system (CNS) depressants,
including sedatives and tranquilizers; and stimulants.
What are opioids and what are the potential consequences of their use
and abuse?
Opioids, include morphine, codeine, and related drugs such as oxycodone
(OxyContin), hydrocodone (Vicodin), and meperidine (Demerol) and are commonly
prescribed to relieve pain. Opioids can produce drowsiness and, in higher
doses, depress respiration. Opioid drugs also can cause euphoria.
Taken as prescribed, opioids can be used to manage pain effectively without
untoward side effects. Chronic use of opioids can result in tolerance,
which means that users must take higher doses to achieve the same effects.
Long-term use also can lead to physical dependence and addiction; withdrawal
can occur when an individual discontinues use of the drugs. Withdrawal
symptoms may include restlessness, muscle and bone pain, insomnia, diarrhea,
vomiting, cold flashes with goose bumps, and involuntary leg movements.
Individuals who are addicted to opioids are more likely to overdose on
the drugs, which could be fatal.
What are CNS depressants and what are the potential consequences of their
use and abuse?
Among the most commonly prescribed CNS depressants are barbiturates, such
as mephobarbital (Mebaral) and pentobarbital sodium (Nembutal), which
are prescribed to treat anxiety, tension, and sleep disorders; and benzodiazepines,
such as diazepam (Valium) and alprazolam (Xanax), which typically are
prescribed to treat anxiety, acute stress reactions, and panic attacks.
Other benzodiazepines, such as triazolam (Halcion) and estazolam (ProSom),
are prescribed for short-term treatment of sleep disorders.
Although the various classes of CNS depressants work differently, they
all produce a beneficial drowsy or calming effect in individuals suffering
from sleep disorders or anxiety. If one uses these drugs over a long period
of time, the body will develop tolerance, and larger doses will be needed
to achieve the initial effects. In addition, continued use can lead to
physical dependence and, when use is reduced or stopped, withdrawal. Both
barbiturates and benzodiazepines have the potential for abuse and should
be used only as prescribed. As with opioids, overdose of these drugs can
be fatal.
What are stimulants and what are the potential consequences of their
use and abuse?
Stimulants enhance brain activity, increasing alertness, attention, and
energy, raising blood pressure, and elevating heart rate and respiration.
Stimulants such as methylphenidate (Ritalin) and dextroamphetamine (Dexedrine)
are prescribed for the treatment of narcolepsy, attention-deficit/hyperactivity
disorder, and depression that has not responded to other treatments. They
also may be used for short-term treatment of obesity.
Individuals may become addicted to the sense of well-being and enhanced
energy that stimulants can generate. Taking high doses of stimulants repeatedly
over a short time, however, can lead to feelings of hostility or paranoia.
Additionally, taking high doses of stimulants may result in dangerously
high body temperatures and an irregular heartbeat.
Source: National Institute On Drug Addiction
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